LV-320 is primarily used in research settings as a pharmacological tool to study the kappa opioid receptor (KOR) system. It acts as a selective antagonist for KOR, making it valuable for investigating the receptor's role in various physiological and pathological processes. Researchers utilize LV-320 to explore its potential in modulating pain perception, mood disorders, and addiction pathways. Its application extends to preclinical studies aimed at understanding the therapeutic implications of KOR antagonism in conditions such as depression, anxiety, and substance abuse. Additionally, LV-320 helps in elucidating the complex signaling mechanisms of KOR, contributing to the development of novel treatments targeting this receptor.