tert-Butyl ((1H-indol-5-yl)methyl)carbamate is primarily used in organic synthesis and pharmaceutical research. It serves as a key intermediate in the development of various biologically active compounds, particularly those targeting neurological and psychiatric disorders. The indole moiety in its structure makes it valuable for synthesizing molecules that interact with serotonin receptors, which are critical in treating conditions like depression, anxiety, and migraines. Additionally, it is utilized in the preparation of peptidomimetics and other drug candidates, where the tert-butyl carbamate group acts as a protecting group for amines during multi-step synthetic processes. Its application extends to the study of enzyme inhibitors and the development of novel therapeutic agents.