Used in advanced organic synthesis as a key intermediate in the preparation of complex natural products, particularly in the development of vitamin D analogs and other secosteroidal compounds. Its highly functionalized structure, featuring a bicyclic indene core, triene system, and protected hydroxyl groups, enables selective transformations for constructing stereochemically defined rings and side chains. Commonly employed in pharmaceutical research for optimizing bioactive molecules with immunomodulatory, anti-inflammatory, anticancer, or bone health properties. The silyl protecting groups (TBS) allow stepwise deprotection and coupling, making it valuable in multi-step syntheses where precision in stereochemistry is critical.