Used as a key reagent in the synthesis of trifluoromethoxy aromatic compounds, which are important building blocks in pharmaceuticals and agrochemicals. It serves as a source of the trifluoromethoxy (OCF₃) group in radical and transition metal-catalyzed reactions, enabling the introduction of this highly stable and lipophilic moiety into organic molecules. Its application is particularly valuable in drug discovery, where the OCF₃ group enhances metabolic stability, membrane permeability, and binding affinity. Also employed in materials science for modifying electronic properties of organic semiconductors.