n-Hexyllithium is primarily used as a strong base and nucleophile in organic synthesis. It is commonly employed in the formation of carbon-carbon bonds, particularly in the preparation of organolithium compounds. This chemical is highly reactive with a variety of organic substrates, making it useful in polymerization reactions, such as the anionic polymerization of styrene and dienes to produce synthetic rubbers and plastics. Additionally, it serves as a key reagent in the synthesis of complex organic molecules, including pharmaceuticals and fine chemicals, where precise control over molecular structure is required. Its ability to deprotonate weakly acidic protons also makes it valuable in the generation of carbanions for further chemical transformations.