(±)9-HODE is widely studied for its role in biological processes, particularly in inflammation and oxidative stress. It is a major oxidation product of linoleic acid and is often used as a biomarker to assess lipid peroxidation in various diseases, including cardiovascular disorders and cancer. In research, it helps in understanding the mechanisms of oxidative damage and the impact of reactive oxygen species on cellular functions. Additionally, (±)9-HODE has been investigated for its potential involvement in signaling pathways that regulate immune responses and cell proliferation. Its applications extend to studying the effects of dietary fats on health, as it provides insights into how polyunsaturated fatty acids are metabolized and contribute to disease progression.