Dimedone dioxime is primarily used in analytical chemistry as a reagent for the detection and determination of metal ions, particularly nickel and palladium. It forms stable, colored complexes with these metals, making it valuable for qualitative and quantitative analysis. In organic synthesis, it serves as a precursor or intermediate in the preparation of various heterocyclic compounds. Additionally, it is employed in research studies to investigate reaction mechanisms and to synthesize specialized organic molecules. Its ability to act as a chelating agent also makes it useful in coordination chemistry for studying metal-ligand interactions.