Formaldoxime hydrochloride is primarily used in analytical chemistry as a reagent for the detection and determination of metal ions, particularly nickel and cobalt. It forms stable complexes with these metals, enabling their identification and quantification in various samples. This compound is also employed in organic synthesis as a building block for the preparation of other chemicals, including oximes and hydrazones. Additionally, it finds application in research laboratories for studying reaction mechanisms and developing new synthetic methodologies. Its role in these processes highlights its importance in both industrial and academic settings.