Palladium on carbon
moistened with water, 10% Pd basis (based on dry substance)
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Widely used as a heterogeneous catalyst in organic synthesis, particularly for hydrogenation reactions. It efficiently promotes the addition of hydrogen to alkenes, alkynes, nitriles, imines, and carbonyl-containing compounds under mild conditions. Commonly employed in the reduction of nitro groups to amines, which is crucial in pharmaceutical manufacturing. Also used in deprotection steps, such as removing benzyl groups from amines or alcohols in complex molecule synthesis. Its solid support allows for easy separation from reaction mixtures, enabling reuse in industrial processes. Frequently applied in the production of fine chemicals, agrochemicals, and active pharmaceutical ingredients (APIs) due to its high activity and selectivity.
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