Used as a highly efficient catalyst in cross-coupling reactions, particularly in Buchwald–Hartwig amination, enabling the formation of carbon–nitrogen bonds. It is effective for the amination of aryl chlorides, including sterically hindered and electron-rich substrates, under mild conditions. Its robust performance allows for high yields in the synthesis of complex amines, pharmaceuticals, and functional materials. The ligand structure enhances catalyst stability and reactivity, making it suitable for late-stage functionalization in drug discovery and industrial-scale applications.