Widely used as a precatalyst in cross-coupling reactions, especially in Buchwald–Hartwig amination and Suzuki–Miyaura coupling. It enables efficient carbon–nitrogen and carbon–carbon bond formation under mild conditions. Its high reactivity and selectivity make it suitable for synthesizing complex molecules, including pharmaceuticals, agrochemicals, and functional materials. The ligand structure enhances palladium stability and promotes rapid oxidative addition, improving catalytic turnover. Often used with mild bases and in low catalyst loadings, it supports scalable and industrially viable processes.