Salicylaldehyde thiosemicarbazone palladium(II) chloride finds significant application in catalysis, particularly in organic synthesis. It is used as a catalyst in various cross-coupling reactions, such as Suzuki and Heck reactions, which are essential for forming carbon-carbon bonds in pharmaceutical and fine chemical industries. Its stability and efficiency make it a preferred choice for these transformations. Additionally, it is explored in material science for the development of coordination polymers and metal-organic frameworks (MOFs), which have potential uses in gas storage, separation, and catalysis. The compound also shows promise in biomedical research, where it is studied for its potential anticancer properties due to its ability to interact with biological molecules and inhibit certain enzymes involved in cancer progression.