AGK-2 is primarily utilized in biochemical and pharmacological research due to its role as a selective inhibitor of tankyrase enzymes, which are involved in various cellular processes, including Wnt signaling pathway regulation. By inhibiting tankyrase, AGK-2 helps researchers study the effects of Wnt signaling modulation, which is crucial in understanding cancer development, stem cell maintenance, and tissue regeneration. Additionally, AGK-2 is employed in studies focusing on neurodegenerative diseases, as tankyrase inhibition can impact pathways associated with neuronal health and survival. Its application extends to drug discovery, where it serves as a tool compound to identify potential therapeutic targets for diseases linked to abnormal Wnt signaling or tankyrase activity.