3-Aminobenzamide
98%
Reagent
Code: #117831
Alias
3-aminobenzamide; m-aminobenzamide
CAS Number
3544-24-9
blur_circular Chemical Specifications
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Molecular Information
Weight
136.15 g/mol
Formula
C₇H₈N₂O
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Registry Numbers
EC Number
222-586-9
MDL Number
MFCD00007989
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Physical Properties
Melting Point
115-116 °C(lit.)
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Storage & Handling
Storage
room temperature
description Product Description
3-Aminobenzamide is primarily used as an inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair processes. Its application in research focuses on studying the mechanisms of DNA repair and the role of PARP in cellular responses to DNA damage. It is employed in experimental settings to induce apoptosis in cancer cells by inhibiting PARP, thereby preventing DNA repair and leading to cell death. This makes it a valuable tool in cancer research, particularly in understanding how PARP inhibitors can be used to enhance the effectiveness of chemotherapy and radiation therapy. Additionally, 3-Aminobenzamide is used in studies exploring neurodegenerative diseases, as PARP activation is implicated in neuronal cell death. Its role in modulating inflammation and oxidative stress further extends its utility in biomedical research.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 98-100% |
| Appearance | White to Grey Powder |
| Infrared Spectrum | Conforms To Structure |
| Solubility in Methanol | Pass |
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