A-966492

99%

Reagent Code: #99335
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CAS Number 934162-61-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 324.35 g/mol
Formula C₁₈H₁₇FN₄O
badge Registry Numbers
MDL Number MFCD17215207
inventory_2 Storage & Handling
Storage -20℃

description Product Description

A-966492 is primarily utilized in research settings as a potent and selective inhibitor of PARP-1 and PARP-2 enzymes. Its application is significant in studying the role of PARP enzymes in DNA repair mechanisms, particularly in the context of cancer research. By inhibiting PARP activity, it helps researchers understand how cancer cells respond to DNA damage and explore potential therapeutic strategies. Additionally, it is used in preclinical studies to evaluate the efficacy of PARP inhibitors in enhancing the effects of chemotherapy or radiation therapy, particularly in cancers with defective DNA repair pathways, such as BRCA-mutated cancers.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to off-white powder
Purity 99-100
Solubility 64 mg/mL (DMSO)
Infrared Spectrum Conforms to Structure

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿6,800.00
A-966492
A-966492 is primarily utilized in research settings as a potent and selective inhibitor of PARP-1 and PARP-2 enzymes. Its application is significant in studying the role of PARP enzymes in DNA repair mechanisms, particularly in the context of cancer research. By inhibiting PARP activity, it helps researchers understand how cancer cells respond to DNA damage and explore potential therapeutic strategies. Additionally, it is used in preclinical studies to evaluate the efficacy of PARP inhibitors in enhancing the effects of chemotherapy or radiation therapy, particularly in cancers with defective DNA repair pathways, such as BRCA-mutated cancers.
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