Amino-PEG5-alcohol is widely used in bioconjugation and drug delivery systems due to its hydrophilic PEG spacer and reactive amino group. It serves as a linker to improve solubility, stability, and biocompatibility of therapeutic compounds. In peptide synthesis, it enhances the pharmacokinetic properties of peptides by reducing immunogenicity and increasing circulation time. It is also utilized in the development of antibody-drug conjugates (ADCs) to connect cytotoxic drugs to antibodies, ensuring targeted delivery to cancer cells. Additionally, it plays a role in surface modification of nanoparticles and biomaterials, facilitating functionalization for specific applications in diagnostics and tissue engineering.