MBHA resin is widely used in solid-phase peptide synthesis (SPPS) as a solid support material. Its primary application lies in the synthesis of C-terminal amidated peptides, where it serves as an anchor for the growing peptide chain. The resin is particularly valued for its stability under acidic conditions, making it suitable for cleavage and deprotection steps in peptide synthesis. Additionally, MBHA resin is employed in the production of peptide libraries for drug discovery and biochemical research, enabling high-throughput screening of peptide sequences. Its compatibility with various coupling reagents and solvents further enhances its utility in peptide chemistry.