Used in organic synthesis as a coupling reagent for peptide bond formation, particularly effective in solid-phase peptide synthesis due to its stability and high reactivity. Commonly applied in the preparation of pharmaceutical intermediates and bioconjugates where efficient amide bond formation is required. Also utilized in the synthesis of small molecule drugs and macromolecular assemblies, offering high yields with minimal racemization. Suitable for automated synthesis platforms and compatible with a wide range of protecting groups and solvents.