Melittin (Pure Powder)™ is a high-purity cosmetic peptide powder for high-potency antimicrobial peptide for acne-prone and blemish-prone cosmetic R&D. It is intended for leave-on cosmetic formulations where a low ppm level of a targeted peptide can be dispersed accurately and protected during processing.

For this ingredient, the evidence should be framed carefully: Melittin is biologically potent and can be irritating/cytolytic at unsuitable levels; use very low-dose R&D framing and require irritation/safety validation. The best public support for many cosmetic peptides comes from exact-INCI studies when available, peptide-family analogs, in vitro/ex vivo models, supplier dossiers, or finished-formula testing.

This material should be treated as a concentrated peptide active, not as a bulk functional additive. Prepare a pre-diluted stock solution for accurate weighing, confirm HPLC recovery in the final base when claims are important, and validate irritation/stability for the intended use area.

Product Description: Melittin (Pure Powder) is suitable for professional cosmetic R&D in serums, gels, creams, masks, scalp products, and other leave-on systems selected according to its benefit profile. It should be positioned with cautious cosmetic language such as helps support, improves the appearance of, or conditions the skin/hair, rather than treatment-style claims.

Usage: High-potency antimicrobial peptide for acne-prone and blemish-prone cosmetic r&d. Suitable for serum, gel, cream/lotion, mask, and targeted leave-on products selected for the claim area.

Mixing method:

- Pre-dissolve in purified water, water/propanediol, water/butylene glycol, or water/glycerin before adding to the main batch.

- Add at the final step during cool-down when the formula is below 40°C. Avoid hot emulsification, hot-fill processing, and prolonged heating.

- Recommended finished-product pH is 5.0-7.0 unless product-specific stability data support a wider range.

- Confirm clarity, preservative compatibility, peptide recovery, and irritation profile in the final formula, especially for eye, lash, scalp, acne-prone, or sensitive-skin products.

Usage rate: 0.0001-0.001% of pure peptide powder. Start at the low end for first prototypes and adjust by assay, stability, irritation, and claim substantiation.

Product characteristics: White to off-white cosmetic peptide powder.

Solubility: Best handled through a water/glycol stock solution; dispersible in cream or gel bases. Acylated peptides may be amphiphilic but should not be assumed to dissolve directly in oils without validation.

Storage: Store tightly closed, protected from moisture. Keep refrigerated at 2-8°C for long-term storage; avoid repeated opening and freeze-thaw cycling.