Acetyl Decapeptide-3
Acetyl Decapeptide-3™ is a high-purity cosmetic peptide powder for growth-factor-inspired skin-renewal, smoother-looking texture, and visible firmness support. It is intended for leave-on cosmetic formulations where a low ppm level of a targeted peptide can be dispersed accurately and protected during processing.
For this ingredient, the evidence should be framed carefully: this peptide is commonly described as a biomimetic bFGF-like cosmetic peptide, but it should not be described as replacing a growth factor; exact public clinical evidence is limited. The best public support for many cosmetic peptides comes from exact-INCI studies when available, peptide-family analogs, in vitro/ex vivo models, supplier dossiers, or finished-formula testing.
This material should be treated as a concentrated peptide active, not as a bulk functional additive. Prepare a pre-diluted stock solution for accurate weighing, confirm HPLC recovery in the final base when claims are important, and validate irritation/stability for the intended use area.
Product Description: Acetyl Decapeptide-3 is suitable for professional cosmetic R&D in serums, gels, creams, masks, scalp products, and other leave-on systems selected according to its benefit profile. It should be positioned with cautious cosmetic language such as helps support, improves the appearance of, or conditions the skin/hair, rather than treatment-style claims.
| Area | Technical basis | Implication |
|---|---|---|
| Benefit focus | growth-factor-inspired skin-renewal, smoother-looking texture, and visible firmness support | Use cosmetic support language; do not imply drug treatment. |
| Evidence scope | this peptide is commonly described as a biomimetic bFGF-like cosmetic peptide, but it should not be described as replacing a growth factor; exact public clinical evidence is limited. | Use exact-INCI data only when available; otherwise state analog/family scope. |
| Formula fit | Water/glycol stock, cool-down addition, mild pH. | Protect peptide recovery, clarity, and sensory comfort. |
Usage: Growth-factor-inspired skin-renewal, smoother-looking texture, and visible firmness support. Suitable for serum, gel, cream/lotion, mask, and targeted leave-on products selected for the claim area.
Mixing method:
- Pre-dissolve in purified water, water/propanediol, water/butylene glycol, or water/glycerin before adding to the main batch.
- Add at the final step during cool-down when the formula is below 40°C. Avoid hot emulsification, hot-fill processing, and prolonged heating.
- Recommended finished-product pH is 5.0-7.0 unless product-specific stability data support a wider range.
- Confirm clarity, preservative compatibility, peptide recovery, and irritation profile in the final formula, especially for eye, lash, scalp, acne-prone, or sensitive-skin products.
Usage rate: 0.001-0.01% of pure peptide powder. Start at the low end for first prototypes and adjust by assay, stability, irritation, and claim substantiation.
Product characteristics: White to off-white cosmetic peptide powder.
Solubility: Best handled through a water/glycol stock solution; dispersible in cream or gel bases. Acylated peptides may be amphiphilic but should not be assumed to dissolve directly in oils without validation.
Storage: Store tightly closed, protected from moisture. Keep refrigerated at 2-8°C for long-term storage; avoid repeated opening and freeze-thaw cycling.
- White to off-white powder
- Fridge (1-10C)
- 12 Months from manufacturing or testing date.
- 0.01% - 0.02%
- 0.01%
- Add at last step. Avoid temperature above 40C.
- Heat Tolerant
- 5.00 - 7.00
- Soluble in Water
- Anti-Aging Ingredient, Serum, Cream, Clear Gel
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