Nonapeptide-1
Nonapeptide-1 is a high-purity cosmetic peptide powder for alpha-MSH/MC1R-pathway brightening, uneven tone, and visible spot-appearance formulas.
Physical form: This product is supplied as a freeze-dried powder.
Nonapeptide-1 is commonly positioned as an alpha-MSH antagonist peptide, making it a strong active story for formulas that target melanin signaling, dullness, uneven tone, and localized dark-spot appearance. It is best used in leave-on serums, gels, creams, masks, and targeted tone-correcting products.
Product Description: Use Nonapeptide-1 when the formula needs a modern peptide brightening story beyond conventional acids and botanical extracts. The powder format gives formulators full control over stock solution concentration, pH, preservative system, peptide recovery, and final texture.
| Formula target | Recommended positioning |
|---|---|
| Brightening | Peptide-based brightening support through alpha-MSH/MC1R pathway positioning. |
| Uneven tone | Suitable for daily leave-on products targeting dullness and uneven-looking complexion. |
| Spot appearance | Useful in targeted formulas for the appearance of dark spots and localized discoloration. |
Usage: Brightening serums, tone-evening gels, creams, lotions, masks, spot-care products, and targeted leave-on peptide treatments.
Mixing method:
- Pre-dissolve in purified water, water/propanediol, water/butylene glycol, or water/glycerin before adding to the main batch.
- Add at the final step during cool-down when the formula is below 40°C. Avoid hot emulsification, hot-fill processing, and prolonged heating.
- Recommended finished-product pH is 5.0-7.0.
- Confirm clarity, preservative compatibility, peptide recovery, color stability, and irritation profile in the final formula.
Usage rate: 0.001-0.01% pure peptide powder. Start at the low end for first prototypes and adjust by assay, stability, irritation, and claim substantiation.
Product characteristics: white to off-white cosmetic peptide powder.
Solubility: Best handled through a water/glycol stock solution; dispersible in cream or gel bases. Do not assume direct oil solubility without validation.
Storage: Store tightly closed, protected from moisture. Keep refrigerated at 2-8°C for long-term storage; avoid repeated opening and freeze-thaw cycling.
- White to off-white powder
- Fridge (1-10C)
- 24 Months from manufacturing or testing date.
- 0.01% - 0.02%
- 0.01%
- Add at last step. Avoid temperature above 40C.
- Avoid heat above 70C
- 5.00 - 7.00
- Soluble in Water
- Skin Brightening, Serum, Cream, Clear Gel
- -
| Test Name | Specification |
|---|---|
| Appearance | White or off-white powder |
| Molecular Ion Mass | 1206.5 |
| Purity (HPLC) | NLT 98.0% |
| Acetic acid Content (HPLC) | NMT 15.0% |
| Water Content (K.F) | NMT 8.0% |
| pH (1% Water Soln.) | 5.5-7.5 |
| Peptide Content | NLT 80.0% |
| Solubility | NLT 100mg/ml (H₂O) |
| Storage | Store at 25°C for transportation; Store at 2°C to 8°C for long term storage. |
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