Used primarily as a lipid-lowering agent to manage high cholesterol levels, Probucol decreases both LDL and HDL cholesterol, helping to reduce the risk of cardiovascular diseases by lowering LDL levels and preventing the oxidation of LDL particles, a key factor in atherosclerosis. However, the reduction in HDL cholesterol is a noted limitation. It is also studied for its potent antioxidant properties, which may protect against oxidative stress-related conditions. Additionally, it has been explored in research for treating conditions like Alzheimer’s disease and diabetic complications due to its anti-inflammatory and neuroprotective effects. Its use is limited in many regions due to side effects, such as prolongation of the QT interval, and the availability of more effective alternatives like statins.