10-Deacetylbaccatin III (10-DAB)
10mM in DMSO
- Product Code: 168897
CAS:
32981-86-5
| Molecular Weight: | 544.59 g./mol | Molecular Formula: | C₂₉H₃₆O₁₀ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00132913 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily as a key starting material in the semi-synthesis of anticancer drugs, especially paclitaxel (Taxol) and docetaxel (Taxotere). These drugs stabilize microtubules, inhibiting cell division and inducing apoptosis in cancer cells. 10-DAB is preferred over direct extraction of paclitaxel due to higher availability from renewable sources like yew tree needles. It allows for scalable, cost-effective production of taxane-based chemotherapeutics used in treating breast, ovarian, lung, and other cancers. Its structural complexity makes it ideal for targeted chemical modifications to develop new derivatives with improved solubility, efficacy, or reduced resistance.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿21,580.00 |
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10-Deacetylbaccatin III (10-DAB)
Used primarily as a key starting material in the semi-synthesis of anticancer drugs, especially paclitaxel (Taxol) and docetaxel (Taxotere). These drugs stabilize microtubules, inhibiting cell division and inducing apoptosis in cancer cells. 10-DAB is preferred over direct extraction of paclitaxel due to higher availability from renewable sources like yew tree needles. It allows for scalable, cost-effective production of taxane-based chemotherapeutics used in treating breast, ovarian, lung, and other cancers. Its structural complexity makes it ideal for targeted chemical modifications to develop new derivatives with improved solubility, efficacy, or reduced resistance.
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