N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
98%
- Product Code: 218707
CAS:
503610-43-3
| Molecular Weight: | 463.52 g./mol | Molecular Formula: | C₂₂H₂₆FN₃O₅S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 131℃ | Boiling Point: | 695.0±65.0℃(Predicted) |
| Density: | 1.387 g/cm3 | Storage Condition: | -20℃ |
Product Description:
Widely used in the management of hypercholesterolemia, this compound functions as a potent inhibitor of HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively lowers low-density lipoprotein (LDL) cholesterol and total cholesterol levels in the bloodstream, reducing the risk of cardiovascular diseases such as atherosclerosis, myocardial infarction, and stroke. Its high bioavailability and long half-life allow for once-daily dosing, improving patient compliance. The compound is particularly effective in patients who do not achieve target cholesterol levels through diet and lifestyle changes alone. It is also used in combination with other lipid-lowering agents for enhanced therapeutic effect. Due to its impact on lipid metabolism, it plays a critical role in both primary and secondary prevention of coronary heart disease.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿8,340.00 |
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| 0.050 G | 10-20 days | ฿22,120.00 |
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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Widely used in the management of hypercholesterolemia, this compound functions as a potent inhibitor of HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively lowers low-density lipoprotein (LDL) cholesterol and total cholesterol levels in the bloodstream, reducing the risk of cardiovascular diseases such as atherosclerosis, myocardial infarction, and stroke. Its high bioavailability and long half-life allow for once-daily dosing, improving patient compliance. The compound is particularly effective in patients who do not achieve target cholesterol levels through diet and lifestyle changes alone. It is also used in combination with other lipid-lowering agents for enhanced therapeutic effect. Due to its impact on lipid metabolism, it plays a critical role in both primary and secondary prevention of coronary heart disease.
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