(2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

≥95%

Reagent Code: #235621
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CAS Number 137234-63-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 349.31 g/mol
Formula C₁₆H₁₄F₃N₅O
thermostat Physical Properties
Boiling Point 508.6±60.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, stored in inert gas

description Product Description

Used primarily as an antifungal agent in the treatment of fungal infections, especially those caused by Candida and Aspergillus species. It functions by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, through the blockade of lanosterol 14α-demethylase, an enzyme dependent on cytochrome P450. This disruption leads to increased membrane permeability and ultimately fungal cell death. Due to its broad-spectrum activity and favorable pharmacokinetic profile, it is administered orally or intravenously in systemic fungal infections, including invasive candidiasis and aspergillosis. It is particularly valuable in immunocompromised patients, such as those undergoing chemotherapy or organ transplantation, where fungal infections pose a significant risk.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿20,100.00
inventory 250mg
10-20 days ฿40,190.00
inventory 1g
10-20 days ฿92,510.00

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