2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione
10mM in DMSO
- Product Code: 239123
Alias:
Reaction stops; thalidomide
CAS:
50-35-1
| Molecular Weight: | 258.23 g./mol | Molecular Formula: | C₁₃H₁₀N₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00153873 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Widely used in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is particularly important in the development of cereblon E3 ligase modulators, which are a class of therapeutics used in treating multiple myeloma and other hematological cancers. Its structure enables selective protein degradation through the ubiquitin-proteasome system, making it valuable in targeted cancer therapy. Additionally, it is used in the design of small-molecule drugs that can recruit specific disease-causing proteins for degradation. Due to its role in enhancing drug specificity and efficacy, it is a critical scaffold in modern drug discovery, especially in oncology and inflammatory disease research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿7,200.00 |
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2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione
Widely used in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is particularly important in the development of cereblon E3 ligase modulators, which are a class of therapeutics used in treating multiple myeloma and other hematological cancers. Its structure enables selective protein degradation through the ubiquitin-proteasome system, making it valuable in targeted cancer therapy. Additionally, it is used in the design of small-molecule drugs that can recruit specific disease-causing proteins for degradation. Due to its role in enhancing drug specificity and efficacy, it is a critical scaffold in modern drug discovery, especially in oncology and inflammatory disease research.
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