2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione

10mM in DMSO

Reagent Code: #239123
label
Alias Reaction stops; thalidomide
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CAS Number 50-35-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 258.23 g/mol
Formula C₁₃H₁₀N₂O₄
badge Registry Numbers
MDL Number MFCD00153873
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Widely used in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is particularly important in the development of cereblon E3 ligase modulators, which are a class of therapeutics used in treating multiple myeloma and other hematological cancers. Its structure enables selective protein degradation through the ubiquitin-proteasome system, making it valuable in targeted cancer therapy. Additionally, it is used in the design of small-molecule drugs that can recruit specific disease-causing proteins for degradation. Due to its role in enhancing drug specificity and efficacy, it is a critical scaffold in modern drug discovery, especially in oncology and inflammatory disease research.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿7,200.00

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