Sulfabenzamide is primarily used as an antibacterial agent, particularly in the treatment of infections caused by susceptible bacteria. It is often incorporated into topical formulations, such as creams or ointments, for managing vaginal infections, including bacterial vaginosis and other gynecological conditions. Its antibacterial properties help inhibit the growth of bacteria by interfering with their metabolic processes. Additionally, it is sometimes combined with other sulfonamides to enhance its efficacy and broaden its spectrum of activity. Its use in topical applications ensures localized treatment with minimal systemic absorption, reducing the risk of side effects.