Used as a reference standard in pharmaceutical analysis to support the development, quality control, and stability testing of paliperidone-based drug formulations. It aids in the identification and quantification of metabolites and impurities during metabolic studies and bioanalytical assays. Commonly employed in HPLC and LC-MS methods to ensure accurate detection of paliperidone and its oxidative metabolites in biological samples. Also utilized in research settings to study metabolic pathways and degradation products of antipsychotic agents.