Hexafluoro-2-(p-tolyl)isopropanol
98%
Reagent
Code: #193813
CAS Number
2010-61-9
science Other reagents with same CAS 2010-61-9
blur_circular Chemical Specifications
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Molecular Information
Weight
258.16 g/mol
Formula
C₁₀H₈F₆O
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Registry Numbers
MDL Number
MFCD00015357
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Physical Properties
Boiling Point
181-182 °C
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Storage & Handling
Density
1.25 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its unique trifluoromethyl group arrangement. Its high lipophilicity and electron-withdrawing properties make it valuable in modifying drug molecules to improve metabolic stability and bioavailability. Commonly employed in the preparation of fluorinated building blocks for medicinal chemistry, especially in the development of central nervous system agents and anti-inflammatory compounds. Also utilized in chiral synthesis where the alcohol functionality serves as a directing group or chiral auxiliary. Its stability under various reaction conditions allows for broad compatibility in multi-step organic transformations.
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