(4R,5R,6S)-4-Nitrobenzyl 3-((diphenoxyphosphoryl)oxy)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

97%

Reagent Code: #230131
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CAS Number 90776-59-3

science Other reagents with same CAS 90776-59-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 594.51 g/mol
Formula C₂₉H₂₇N₂O₁₀P
thermostat Physical Properties
Melting Point 129-131°C
Boiling Point 722.4°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of beta-lactam antibiotics, particularly in the preparation of carbapenem-class antimicrobial agents. Its structure allows for selective functionalization at multiple sites, making it valuable in constructing complex antibiotic molecules with enhanced stability and broad-spectrum activity. The diphenoxyphosphoryl group acts as a protecting and activating moiety during coupling reactions, while the nitrobenzyl group enables photolytic or reductive deprotection under mild conditions. This compound is instrumental in solid-phase and solution-phase peptide coupling strategies aimed at developing new-generation antibiotics with resistance to beta-lactamase degradation.

Available Sizes & Pricing

Size Availability Unit Price Quantity
250mg
10-20 days ฿330.00
1g
10-20 days ฿770.00
5g
10-20 days ฿2,840.00
25g
10-20 days ฿10,150.00
100g
10-20 days ฿31,880.00
(4R,5R,6S)-4-Nitrobenzyl 3-((diphenoxyphosphoryl)oxy)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
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Used as a key intermediate in the synthesis of beta-lactam antibiotics, particularly in the preparation of carbapenem-class antimicrobial agents. Its structure allows for selective functionalization at multiple sites, making it valuable in constructing complex antibiotic molecules with enhanced stability and broad-spectrum activity. The diphenoxyphosphoryl group acts as a protecting and activating moiety during coupling reactions, while the nitrobenzyl group enables photolytic or reductive deprotection under mild conditions. This compound is instrumental in solid-phase and solution-phase peptide coupling strategies aimed at developing new-generation antibiotics with resistance to beta-lactamase degradation.
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