(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
98%
science Other reagents with same CAS 201856-57-7
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description Product Description
Used as an intermediate in the synthesis of β-lactam antibiotics, particularly in the preparation of carbapenem and penem class antibiotics. The compound’s protected aldehyde and azetidinone ring make it valuable for constructing the core scaffold of these antibiotics with high stereochemical control. The 1-ethoxyethoxy group acts as a masked aldehyde, allowing selective deprotection under mild acidic conditions to enable further chain elongation. Its tert-butyloxycarbonyl (Boc) protection facilitates compatibility with peptide coupling strategies, making it suitable for multi-step syntheses in medicinal chemistry. Commonly employed in research settings for developing novel antimicrobial agents.
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