TFAP is widely used in the synthesis of fluorinated organic compounds, particularly in pharmaceutical and agrochemical industries. Its high reactivity allows for efficient introduction of fluorinated groups into complex molecules, enhancing metabolic stability and bioavailability. It serves as a key reagent in electrophilic fluorination processes, making it valuable in the development of radiotracers for PET imaging. Due to its ability to operate under mild conditions, TFAP is preferred in sensitive multi-step syntheses where preserving functional group integrity is crucial. It is also employed in materials science for modifying surface properties of polymers, improving their chemical resistance and thermal stability.