tert-butyl (7,7-difluorobicyclo[4.1.0]heptan-1-yl)carbamate

95%

Reagent Code: #241835

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 247.14 g/mol
Formula C₁₂H₁₉F₂NO₂
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its structure features a strained bicyclic [4.1.0] system with geminal difluoride substituents at the 7-position, which enhance metabolic stability and membrane permeability in drug candidates. The tert-butyl carbamate (Boc) group serves as a protecting group for the amine at the 1-position, enabling precise control over synthetic steps, especially in constructing chiral centers or highly specific molecules. Commonly employed in the development of enzyme inhibitors and receptor modulators, where fluorinated scaffolds improve binding affinity and pharmacokinetic properties. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to the rigidity, steric profile, and unique reactivity of the bicyclic system.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿6,336.00
inventory 1g
10-20 days ฿32,400.00
inventory 100mg
10-20 days ฿4,158.00
tert-butyl (7,7-difluorobicyclo[4.1.0]heptan-1-yl)carbamate
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Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its structure features a strained bicyclic [4.1.0] system with geminal difluoride substituents at the 7-position, which enhance metabolic stability and membrane permeability in drug candidates. The tert-butyl carbamate (Boc) group serves as a protecting group for the amine at the 1-position, enabling precise control over synthetic steps, especially in constructing chiral centers or highly s

Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its structure features a strained bicyclic [4.1.0] system with geminal difluoride substituents at the 7-position, which enhance metabolic stability and membrane permeability in drug candidates. The tert-butyl carbamate (Boc) group serves as a protecting group for the amine at the 1-position, enabling precise control over synthetic steps, especially in constructing chiral centers or highly specific molecules. Commonly employed in the development of enzyme inhibitors and receptor modulators, where fluorinated scaffolds improve binding affinity and pharmacokinetic properties. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to the rigidity, steric profile, and unique reactivity of the bicyclic system.

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