(2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone
98%
science Other reagents with same CAS 141645-23-0
blur_circular Chemical Specifications
description Product Description
This compound is a key synthetic intermediate in the production of Dronedarone, an antiarrhythmic medication used to treat atrial fibrillation and other cardiovascular arrhythmias. Its structure, featuring a 2-butyl-5-nitrobenzofuran-3-yl group attached to a 4-[3-(dibutylamino)propoxy]phenyl methanone, is critical for subsequent steps like nitro reduction to amine and acetylation at the 5-position to form the active drug. Primarily employed in medicinal chemistry and pharmaceutical research for developing cardiovascular therapeutics, it interacts with biological targets relevant to cardiac ion channels and receptors. The nitro and benzofuran moieties contribute to its utility in drug synthesis, though direct pharmacological testing of the intermediate is limited. High-purity samples are essential for research and scale-up synthesis.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Yellow oily liquid |
| Purity | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
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