(2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone

98%

Reagent Code: #36341
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CAS Number 141645-23-0

science Other reagents with same CAS 141645-23-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 508.649 g/mol
Formula C₃₀H₄₀N₂O₅
inventory_2 Storage & Handling
Storage room temperature, dry

description Product Description

This compound is a key synthetic intermediate in the production of Dronedarone, an antiarrhythmic medication used to treat atrial fibrillation and other cardiovascular arrhythmias. Its structure, featuring a 2-butyl-5-nitrobenzofuran-3-yl group attached to a 4-[3-(dibutylamino)propoxy]phenyl methanone, is critical for subsequent steps like nitro reduction to amine and acetylation at the 5-position to form the active drug. Primarily employed in medicinal chemistry and pharmaceutical research for developing cardiovascular therapeutics, it interacts with biological targets relevant to cardiac ion channels and receptors. The nitro and benzofuran moieties contribute to its utility in drug synthesis, though direct pharmacological testing of the intermediate is limited. High-purity samples are essential for research and scale-up synthesis.

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Test Parameter Specification
Appearance Yellow oily liquid
Purity 97.5-100%
Infrared Spectrum Conforms to Structure

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Size Availability Unit Price Quantity
inventory 100g
10-20 days ฿19,220.00
inventory 25g
10-20 days ฿7,860.00
inventory 1g
10-20 days ฿720.00
inventory 5g
10-20 days ฿2,280.00

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(2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone
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This compound is a key synthetic intermediate in the production of Dronedarone, an antiarrhythmic medication used to treat atrial fibrillation and other cardiovascular arrhythmias. Its structure, featuring a 2-butyl-5-nitrobenzofuran-3-yl group attached to a 4-[3-(dibutylamino)propoxy]phenyl methanone, is critical for subsequent steps like nitro reduction to amine and acetylation at the 5-position to form the active drug. Primarily employed in medicinal chemistry and pharmaceutical research for developin

This compound is a key synthetic intermediate in the production of Dronedarone, an antiarrhythmic medication used to treat atrial fibrillation and other cardiovascular arrhythmias. Its structure, featuring a 2-butyl-5-nitrobenzofuran-3-yl group attached to a 4-[3-(dibutylamino)propoxy]phenyl methanone, is critical for subsequent steps like nitro reduction to amine and acetylation at the 5-position to form the active drug. Primarily employed in medicinal chemistry and pharmaceutical research for developing cardiovascular therapeutics, it interacts with biological targets relevant to cardiac ion channels and receptors. The nitro and benzofuran moieties contribute to its utility in drug synthesis, though direct pharmacological testing of the intermediate is limited. High-purity samples are essential for research and scale-up synthesis.

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