Shield-1 is widely used in biochemical and genetic research, particularly in studies involving conditional protein stability. It is a small molecule that stabilizes proteins fused to a destabilizing domain, allowing researchers to control protein levels in cells or organisms with precision. This application is especially valuable in experiments where temporal and spatial regulation of protein expression is critical, such as in functional genomics, drug discovery, and developmental biology. Shield-1 is also utilized in live-cell imaging and proteomics to study protein dynamics and interactions. Its ability to rapidly and reversibly modulate protein stability makes it a powerful tool for investigating protein function and signaling pathways in various biological systems.