DC 260126 is a potent and selective inhibitor of Na⁺/K⁺-ATPase. It is primarily used in pharmaceutical research and development for studying ion transport mechanisms, cardiac function, neuronal activity, and related biological pathways. Employed in biochemical assays to probe interactions with Na/K-ATPase pumps, elucidating efficacy, mechanisms of action, and potential as therapeutic agents. Essential in preclinical studies for pharmacokinetics and pharmacodynamics evaluation to advance to clinical trials. Explored for applications in heart failure, cancer, inflammation, and neurological disorders, offering benefits over traditional cardiac glycosides due to lower toxicity.