Halofantrine hydrochloride
≥98%
- Product Code: 100784
CAS:
36167-63-2
| Molecular Weight: | 536.88 g./mol | Molecular Formula: | C₂₆H₃₁Cl₃F₃NO |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
Halofantrine hydrochloride is primarily used in the treatment of malaria, particularly for infections caused by Plasmodium falciparum, which is known for its resistance to other antimalarial drugs. It is effective in areas where chloroquine resistance is prevalent. The compound works by disrupting the parasite's ability to detoxify heme, leading to its accumulation and subsequent death of the parasite. However, due to its potential to cause serious cardiac side effects, such as arrhythmias, it is generally reserved for cases where other treatments have failed or are not suitable. It is administered orally and is often used in combination with other antimalarial agents to enhance efficacy and reduce the risk of resistance development. Careful monitoring of cardiac function is essential during its use.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $593.03 |
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| 0.010 | 10-20 days | $1,146.20 |
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Halofantrine hydrochloride
Halofantrine hydrochloride is primarily used in the treatment of malaria, particularly for infections caused by Plasmodium falciparum, which is known for its resistance to other antimalarial drugs. It is effective in areas where chloroquine resistance is prevalent. The compound works by disrupting the parasite's ability to detoxify heme, leading to its accumulation and subsequent death of the parasite. However, due to its potential to cause serious cardiac side effects, such as arrhythmias, it is generally reserved for cases where other treatments have failed or are not suitable. It is administered orally and is often used in combination with other antimalarial agents to enhance efficacy and reduce the risk of resistance development. Careful monitoring of cardiac function is essential during its use.
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