7-Ethyl-10-hydroxycamptothecin
98%
- Product Code: 110413
Alias:
7-Ethyl-10-Hydroxycamptothecin
CAS:
86639-52-3
| Molecular Weight: | 392.40 g./mol | Molecular Formula: | C₂₂H₂₀N₂O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06762720 | |
| Melting Point: | 217 °C | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
This compound is primarily used in the field of oncology as a potent anticancer agent. It functions by inhibiting the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. By blocking this enzyme, it prevents the cancer cells from dividing and proliferating, leading to their eventual death. It is often utilized in the treatment of various types of cancers, including colorectal, ovarian, and lung cancers. The compound is typically administered intravenously as part of chemotherapy regimens. Its efficacy and safety profile make it a valuable component in the management of advanced or metastatic cancers, often in combination with other chemotherapeutic agents to enhance therapeutic outcomes.
Product Specification:
| Test | Specification |
|---|---|
| Purity (HPLC) | 98-100 |
| Specific Rotation [A]20/D (C=0.2, THF) | 17-26 |
| Water By Karl Fischer | 0-10 |
| Appearance | Off-White To Yellow Powder |
| Solubility In DMSO | Faint Yellow To Yellow, Clear, 1 Mg/Ml |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿500.00 |
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| 1.000 | 10-20 days | ฿2,680.00 |
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| 5.000 | 10-20 days | ฿12,020.00 |
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7-Ethyl-10-hydroxycamptothecin
This compound is primarily used in the field of oncology as a potent anticancer agent. It functions by inhibiting the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. By blocking this enzyme, it prevents the cancer cells from dividing and proliferating, leading to their eventual death. It is often utilized in the treatment of various types of cancers, including colorectal, ovarian, and lung cancers. The compound is typically administered intravenously as part of chemotherapy regimens. Its efficacy and safety profile make it a valuable component in the management of advanced or metastatic cancers, often in combination with other chemotherapeutic agents to enhance therapeutic outcomes.
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