1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
≥95%
- Product Code: 123225
CAS:
151213-15-9
| Molecular Weight: | 389.40 g./mol | Molecular Formula: | C₂₀H₂₁F₂N₃O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD21364378 | |
| Melting Point: | Boiling Point: | 596.909°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, protected from light, stored in an inert gas |
Product Description:
This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of advanced antibiotics. Its structure is particularly effective in the development of fluoroquinolone-class drugs, which are widely used to treat bacterial infections. The presence of the cyclopropyl and difluoro groups enhances its ability to target and inhibit bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial DNA replication. This makes it valuable in creating medications for respiratory, urinary tract, and skin infections. Additionally, its unique pyrrolo-pyridine moiety contributes to improved pharmacokinetic properties, such as better absorption and distribution in the body, making it a preferred choice for drug formulation.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿9,189.00 |
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| 0.250 | 10-20 days | ฿14,733.00 |
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| 1.000 | 10-20 days | ฿36,900.00 |
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1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of advanced antibiotics. Its structure is particularly effective in the development of fluoroquinolone-class drugs, which are widely used to treat bacterial infections. The presence of the cyclopropyl and difluoro groups enhances its ability to target and inhibit bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial DNA replication. This makes it valuable in creating medications for respiratory, urinary tract, and skin infections. Additionally, its unique pyrrolo-pyridine moiety contributes to improved pharmacokinetic properties, such as better absorption and distribution in the body, making it a preferred choice for drug formulation.
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