Pamoic acid
98%
- Product Code: 62058
Alias:
Double citrate, capacid, cinnamic acid, citrate, 2,2`-dicitrate-3,3`-diacid-1,1`dicitrate
CAS:
130-85-8
Molecular Weight: | 388.37 g./mol | Molecular Formula: | C₂₃H₁₆O₆ |
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EC Number: | 204-998-0 | MDL Number: | MFCD00004079 |
Melting Point: | ≥300 °C (dec.) | Boiling Point: | |
Density: | Storage Condition: | room temperature |
Product Description:
Pamoic acid is primarily used in the pharmaceutical industry as a counterion in the formulation of drugs to improve their solubility, stability, and bioavailability. It is commonly employed to create pamoate salts of basic drugs, particularly those used in long-acting injectable formulations. For example, it is used in the production of pamoate salts of antipsychotic medications like paliperidone palmitate and antidepressant drugs such as imipramine pamoate. These formulations allow for controlled and sustained release of the active pharmaceutical ingredient, reducing the frequency of administration and improving patient compliance. Additionally, pamoic acid’s low solubility in water makes it suitable for creating depot injections, which slowly release the drug over an extended period. Its use in drug delivery systems highlights its importance in enhancing therapeutic efficacy and patient outcomes.
Product Specification:
Test | Specification |
---|---|
LOSS ON DRYING | 0 1% |
PURITYNEUTRALIZATION TITRATION | 96.5 103.5% |
APPEARANCE | Off-white to yellow powder |
INFRARED SPECTRUM | Conforms to Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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5.000 | 10-20 days | ฿300.00 |
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25.000 | 10-20 days | ฿520.00 |
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100.000 | 10-20 days | ฿1,500.00 |
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500.000 | 10-20 days | ฿6,680.00 |
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Pamoic acid
Pamoic acid is primarily used in the pharmaceutical industry as a counterion in the formulation of drugs to improve their solubility, stability, and bioavailability. It is commonly employed to create pamoate salts of basic drugs, particularly those used in long-acting injectable formulations. For example, it is used in the production of pamoate salts of antipsychotic medications like paliperidone palmitate and antidepressant drugs such as imipramine pamoate. These formulations allow for controlled and sustained release of the active pharmaceutical ingredient, reducing the frequency of administration and improving patient compliance. Additionally, pamoic acid’s low solubility in water makes it suitable for creating depot injections, which slowly release the drug over an extended period. Its use in drug delivery systems highlights its importance in enhancing therapeutic efficacy and patient outcomes.
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