Oleyloxyethyl phosphorylcholine is widely used in the formulation of personal care and cosmetic products due to its excellent moisturizing and skin-conditioning properties. It helps to improve skin hydration by forming a protective barrier that prevents moisture loss, making it a key ingredient in creams, lotions, and serums. Its biocompatibility and mildness also make it suitable for sensitive skin formulations.

In the pharmaceutical industry, it is utilized as a component in drug delivery systems, particularly in liposomes and micelles, to enhance the solubility and stability of active pharmaceutical ingredients. Its amphiphilic nature allows it to act as an effective emulsifier and stabilizer in various formulations.

Additionally, it finds applications in the development of medical devices and coatings, where it is used to impart biocompatibility and reduce the risk of adverse reactions when in contact with biological tissues. Its ability to mimic natural cell membranes makes it valuable in creating surfaces that resist protein adsorption and cell adhesion, improving the performance of implants and other medical tools.