Tris(3,5-dimethylphenyl)phosphine is primarily utilized as a ligand in coordination chemistry and catalysis. It is particularly effective in transition metal-catalyzed reactions, such as cross-coupling reactions, where it enhances the stability and reactivity of the metal center. This compound is also employed in the synthesis of organometallic complexes, which are crucial in various industrial processes, including the production of fine chemicals and pharmaceuticals. Additionally, its steric and electronic properties make it suitable for use in asymmetric catalysis, enabling the production of enantiomerically pure compounds. The chemical is also explored in material science for the development of advanced polymers and nanomaterials.