Used as a highly effective ligand in palladium-catalyzed cross-coupling reactions, enabling efficient carbon-carbon bond formation in organic synthesis. Particularly valuable in Suzuki-Miyaura and Buchwald-Hartwig aminations, it allows for mild reaction conditions, high yields, and excellent functional group tolerance. Widely applied in pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs), due to its stability and reactivity profile.