2-thio-PAF is primarily utilized in research settings to study platelet-activating factor (PAF) receptors and their signaling pathways. It acts as a thioether analog of PAF, allowing scientists to investigate the role of PAF in inflammatory responses, immune system modulation, and cellular communication. Its structural similarity to PAF enables it to bind to PAF receptors, making it a valuable tool for understanding receptor interactions and developing potential therapeutic agents targeting PAF-mediated processes, such as inflammation and allergic reactions. Additionally, 2-thio-PAF is used in biochemical assays to explore the mechanisms of PAF in various physiological and pathological conditions.