Primarily used in the synthesis of organophosphorus compounds, this chemical serves as a key intermediate in the production of flame retardants, plasticizers, and pesticides. Its reactive phosphoryl and chloro groups make it valuable for creating phosphonate esters, which are essential in various industrial applications. Additionally, it plays a role in the development of nerve agents and chemical weapons, though its use in this context is highly regulated. In research, it is employed to modify surfaces or molecules for specific chemical properties, particularly in materials science and organic synthesis.