Used primarily as a reagent in organic synthesis, phenyl dichlorophosphate is instrumental in the formation of phosphate esters and phosphoramidates. It is widely applied in the production of flame retardants, where it enhances the fire resistance of materials such as plastics and textiles. Additionally, it serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and anticancer drugs. Its role in peptide synthesis is also notable, where it aids in the protection and activation of amino acids. In the field of agrochemicals, it is utilized to create pesticides and herbicides, contributing to crop protection and yield improvement.