4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzyl Alcohol
≥97%
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This chemical is primarily utilized in photoaffinity labeling studies, a technique widely employed in biochemistry and molecular biology to investigate protein-ligand interactions. The compound's diazirine group, when exposed to ultraviolet light, generates a highly reactive carbene intermediate. This intermediate can form covalent bonds with nearby molecules, allowing researchers to "trap" and identify binding partners within complex biological systems. Its benzyl alcohol moiety enhances solubility in aqueous environments, making it suitable for use in biological assays. Additionally, the trifluoromethyl group increases the stability of the diazirine ring, ensuring efficient photolysis. This chemical is particularly valuable in drug discovery, where it helps map binding sites on target proteins and elucidate mechanisms of action for potential therapeutic compounds.
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