Used primarily in chemotherapy for treating various cancers, particularly Hodgkin's lymphoma and non-Hodgkin's lymphoma. It is also effective in managing advanced testicular cancer and some forms of leukemia. The compound works by inhibiting cell division through disruption of microtubule formation in mitotic spindles, leading to cancer cell death. Due to its potency, it is administered under strict medical supervision, often as part of combination therapy regimens. Its use may be limited by side effects such as neurotoxicity and bone marrow suppression.