Yangonin is primarily studied for its potential neuroactive properties, particularly its interaction with the endocannabinoid system. It has shown affinity for cannabinoid receptors in preclinical research, suggesting possible applications in modulating mood, anxiety, and stress responses. Due to this activity, yangonin is investigated for its role in supporting neurological health and cognitive function. It may contribute to the anxiolytic and mild sedative effects associated with kava extracts, traditionally used in herbal medicine for promoting relaxation without significant cognitive impairment. Research is ongoing to explore its potential in natural therapeutics for anxiety and sleep disorders, though clinical evidence remains limited. Its ability to cross the blood-brain barrier enhances its interest for central nervous system-targeted applications.