3-METHYLADENINE
97%
Reagent
Code: #110625
CAS Number
5142-23-4
blur_circular Chemical Specifications
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Molecular Information
Weight
149.15 g/mol
Formula
C₆H₇N₅
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Registry Numbers
MDL Number
MFCD00010531
thermostat
Physical Properties
Melting Point
~ 300°C dec. (Lit.)
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Storage & Handling
Storage
2~8℃, dry
description Product Description
Used primarily in biological research to study autophagy, a cellular degradation process. It acts as an inhibitor of class III phosphatidylinositol 3-kinases (PI3K), which are crucial for autophagosome formation. Researchers employ it to block autophagy in experimental settings, helping to understand its role in cellular homeostasis, disease mechanisms, and cell survival. Additionally, it is utilized in cancer research to investigate the relationship between autophagy and tumor progression or resistance to therapy. Its application extends to studying neurodegenerative diseases, where autophagy plays a significant role in clearing damaged proteins and organelles.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (%) | 96.5-100% |
| Appearance | White to off-white powder |
| Melting Point | 300°C (dec.) |
| Infrared Spectrometry | Conforms To Structure |
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